论文部分内容阅读
目的研究辽东丁香树枝的化学成分。方法系统溶剂法对辽东丁香枝进行提取,并采用柱色谱、薄层色谱等分离手段对其进行分离纯化。水蒸气蒸馏法提取挥发油化学成分,利用GC-MS分析。结果鉴定出6种化合物,分别是:对苯二甲酸二甲酯(化合物1)、3-羟基-乌苏烷-12-烯(化合物2)、熊果酸(化合物3)、4-(2-羟乙基)-苯酚(化合物4)、D-甘露醇(化合物5)、丁香苷(化合物6);挥发油化学成分69种,占挥发油总量的99.86%,含量大的成分为2-甲基-5-(1-甲基乙基)-1-环戊烯醇(14.16%)。结论化合物3、5、6为首次从辽东丁香中分离得到,化合物1、2、4为首次从丁香属植物中分离得到。化合物2和6含量较大,为将来富集这两个化合物提供依据。挥发油中除了烷烃类外,其他类化合物部分成分含有萜类特征,其中烯烃类和氧化物类化合物中倍半萜成分所占比例最大。
Objective To study the chemical constituents of lilac branches in Liaodong. Methods Systematic solvent method was used to extract the clove branch of Liaodong, and its separation was purified by column chromatography and thin layer chromatography. The chemical constituents of volatile oil were extracted by steam distillation and analyzed by GC-MS. As a result, six kinds of compounds were identified: dimethyl terephthalate (Compound 1), 3-hydroxy-ursu-12-ene (Compound 2), ursolic acid (Compound 3), 4- (Compound 4), D-mannitol (compound 5) and syringin (compound 6). There were 69 chemical constituents of volatile oil, accounting for 99.86% of the total volatile oil and 2-methyl 5- (1-methylethyl) -1-cyclopentenol (14.16%). Conclusion Compounds 3, 5 and 6 were isolated from clove liaoning for the first time. Compounds 1, 2 and 4 were isolated from Syringa for the first time. Compound 2 and 6 are larger, providing the basis for enrichment of these two compounds in the future. Volatile oil in addition to alkanes, some other compounds contain terpenoid features, of which olefins and oxides of sesquiterpene components accounted for the largest proportion.