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目的：比较保定、亳州、定州三产地长梗薤白提取物对高脂血症大鼠脂蛋白－胆固醇代谢的影响及其抗氧化作用。方法：复制大鼠高脂血症模型，测定血清脂蛋白－胆固醇及过氧化脂质（ＬＰＯ）含量，观察比较三种产地薤白提取物对高脂血症大鼠脂蛋白－胆固醇代谢的影响及抗氧化作用。结果：三产地长梗薤白提取物能显著降低高脂血症大鼠血清ＴＣ和ＬＤＬ－Ｃ含量，明显降低ＴＧ含量，明显升高血清ＨＤＬ－Ｃ含量，同时能显著降低高脂血症大鼠血清ＬＰＯ含量；组间比较除亳州产薤白提取物升高血清ＨＤＬ－Ｃ较显著外，其他指标组间比较无显著差异。结论：提示三产地长梗薤白提取物均有较强的降血脂作用，此作用产地之间差异不大。
OBJECTIVE: To compare the effects of extracts of long-stemmed indigotica from three production sites in Baoding, Zhangzhou and Dingzhou on lipoprotein-cholesterol metabolism in hyperlipidemic rats and their anti-oxidative effects. METHODS: Rat hyperlipidemia model was duplicated, serum lipoprotein-cholesterol and lipid peroxidation (LPO) levels were determined, and the effects of extracts of Radix Paeoniae alba extracts on lipoprotein-cholesterol metabolism in hyperlipidemic rats were observed and compared. Anti-oxidize effect. RESULTS: The extracts of Tribulus terrestris L. from three production areas could significantly reduce the serum levels of TC and LDL-C in hyperlipidemic rats, significantly reduce the content of TG, significantly increase the serum HDL-C level, and significantly reduce the hyperlipidemic rats. Serum LPO content; between the groups except for the increase of serum HDL-C in Quzhou pupa extract, there was no significant difference between other groups. Conclusion: It is suggested that the extracts from the long-stemmed stem borer of the three producing areas all have strong lipid-lowering effect, and there is no significant difference between the producing areas of this effect.