清肺平喘汤治疗小儿哮喘随机平行对照研究

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[目的]观察清肺平喘汤治疗小儿哮喘疗效。[方法]使用随机平行对照方法,将80例门诊患者按随机数字表法随机分为两组。对照组40例吸氧、平喘、祛痰、抗感染等对症治疗。治疗组40例清肺平喘汤(生石膏15g,炙麻黄、白果、紫苏子各3g,杏仁、地骨皮各6g,地龙4g,黄芩3g,生甘草2g)1剂/d,水煎100mL,早晚口服。连续治疗7d为1疗程。观测临床症状、肺功能(FVC、FEV1、PEF)、不良反应。连续治疗1疗程,判定疗效。[结果]治疗组临床控制21例,显效14例,有效2例,无效3例,总有效率92.50%。对照组临床控制14例,显效10例,有效7例,无效9例,总有效率77.50%。治疗组疗效优于对照组(P<0.05)。肺功能指标(FVC、FEV1、PEF50及FEV1/FVC)两组均显著升高(P<0.05),组间无明显差异(P>0.05)[结论]清肺平喘汤治疗小儿哮喘效果显著,值得推广。 [Objective] To observe the therapeutic effect of Qingfei Pingchuan Decoction on pediatric asthma. [Methods] Using randomized parallel control method, 80 outpatients were randomly divided into two groups according to random number table method. Control group of 40 cases of oxygen, asthma, expectorant, anti-infective symptomatic treatment. The treatment group 40 patients Qingfei Pingchuan Decoction (gypsum 15g, burdock yellow, ginkgo, perilla each 3g, almonds, Digupi 6g, earthworm 4g, Scutellaria 3g, raw licorice 2g) 1 / d, decoction 100mL, morning and evening oral. Continuous treatment 7d for a course of treatment. Clinical symptoms, pulmonary function (FVC, FEV1, PEF) and adverse reactions were observed. Continuous treatment of a course of treatment to determine the efficacy. [Results] In the treatment group, 21 cases were clinically controlled, 14 cases were markedly effective, 2 cases were effective, 3 cases were ineffective and the total effective rate was 92.50%. The control group, clinical control in 14 cases, markedly effective in 10 cases, effective in 7 cases, ineffective in 9 cases, the total effective rate was 77.50%. The treatment group was better than the control group (P <0.05). The pulmonary function indexes (FVC, FEV1, PEF50 and FEV1 / FVC) in both groups were significantly increased (P <0.05), there was no significant difference between the two groups (P> 0.05) [Conclusion] Qingfei Pingchuan Decoction treatment of children with asthma significantly, Worth promoting.
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