论文部分内容阅读
目的了解2011年1月-2012年12月上海市普陀区手足口病病原学特征,为手足口病的防控提供实验室依据。方法采集432例手足口疑似病例的咽拭子、疱疹液,粪便标本共723份,用实时荧光定量PCR方法进行肠道病毒通用型(EV)、肠道病毒71型(EV71)、柯萨奇病毒A组16型(CoxA16)的核酸检测。结果 723份手足口病例标本肠道通用型阳性394份(54.50%),肠道病毒71型(EV71)阳性160份(22.13%),柯萨奇病毒A组16型(CoxA16)阳性165份(22.82%)。结论上海市普陀区手足口病不同时期病原体呈现交替流行,患者年龄分布和时间分布特征明显,对手足口病原体的流行病学分析有助于做好手足口病的防控工作。
Objective To understand the etiological characteristics of HFMD in Putuo District of Shanghai from January 2011 to December 2012 and to provide a laboratory basis for the prevention and control of HFMD. Methods A total of 723 samples of pharyngeal swab, herpes fluid and stool were collected from 432 suspected cases of hand-foot-mouth. Total real-time fluorescence quantitative PCR was used to detect EV, EV71, Virus A Group 16 (CoxA16) Nucleic Acid Detection. Results There were 394 (54.50%) positive samples of 723 cases of HFMD, 160 (22.13%) positive samples of enterovirus 71 (EV71), 165 positive samples of CoxA16 (CoxA16) 22.82%). Conclusion The pathogens of hand-foot-mouth disease in Putuo District of Shanghai City were alternately epidemic. The age distribution and time distribution of the patients were obvious. Epidemiological analysis of hand-foot-mouth pathogens was helpful to prevention and control of hand-foot-mouth disease.