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英国伦敦King’s 医学院MarrisBirthright 胎儿医学研究中心在1990年1月~1991年10月对827例胚胎存活的孕早期(10~14孕周)孕妇进行了前瞻性腹部超声显像检查,发现胎儿颈项部异常液体(超声特征为半透明变——translucency)与胎儿染色体异常之间有密切联系,并将其确定为染色体异常标志。1 材料与方法1.1 材料来源该中心在22个月中,对上述827名孕妇于孕早期拟进行羊水穿刺或取绒毛作胎儿染色体核型分析者作B 超常规检查。孕妇平均
Prospective abdominal ultrasound imaging of 827 pregnant women with embryonic survival (10-14 weeks gestation) from January 1990 to October 1991 was conducted at the Marris Birthright Fetal Medicine Research Center at King’s College of Medicine in King’s, London, UK. The fetal neck region Abnormal fluid (translucent ultrasound features translucency) and fetal chromosomal abnormalities are closely linked, and identified as a sign of chromosomal abnormalities. 1 Materials and Methods 1.1 Source of Materials The center in 22 months, the above 827 pregnant women in the first trimester of pregnancy to be amniocentesis or dehairing for fetal chromosome karyotype analysis for B-routine examination. Pregnant women on average