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利朵卡因原为一种局部麻醉用药,近几年来被应用于治疗和预防急性心肌梗塞时的室性心律失常,从而明显地减少了急性心肌梗塞的死亡率。其作用是抑制心室内蒲氏纤维的自律性,提高心肌对刺激的阈界。它并不延长房室传导和心室内的传导。在应用一般治疗心律失常的剂量时,不影响心脏收缩,不减少心排出量或降低血压。在急性心肌梗塞的病人中,利朵卡因适用于以下情况:(1)频发、多源、连续或出现于心搏早期的室
Lidocaine, a former local anesthetic drug, has been used in recent years to treat and prevent ventricular arrhythmias in acute myocardial infarction, thereby significantly reducing the mortality rate of acute myocardial infarction. Its role is to inhibit the intrinsic self-discipline of the heart Pu-fiber, improve the threshold of myocardial stimulation. It does not extend atrioventricular and ventricular conduction. In the general application of the dose of arrhythmia treatment does not affect the contraction of the heart, does not reduce cardiac output or lower blood pressure. In patients with acute myocardial infarction, lidocaine is suitable for the following situations: (1) frequent, multi-sourced, continuous or in early cardiac chambers