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高尿酸血症及痛风 〔概念〕 尿酸是嘌呤代谢的最终产物,据国内北京等大城市502名正常人的调查,其血清正常值在男性261.7±60μmol/L,女性202.2±53.5μmol/L,当男性血尿酸大于386.62μmol/L,女性大于309.39μmol/L,可诊为高尿酸血症。 痛风是由嘌呤代谢或排泄失常所引起的一组临床综合病征,分原发性和继发性两大类,通常由高尿酸血症而查悉。临床上可表现为急性关节炎、痛风石、尿酸性肾结石或肾功能不全等,上述表现以不同形式组合而出现。
Hyperuricemia and Gout [Concept] Uric acid is the final product of purine metabolism. According to the survey of 502 normal people in Beijing and other big cities, the normal serum values are 261.7 ± 60μmol / L in male and 202.2 ± 53.5μmol / L in female, When male blood uric acid greater than 386.62μmol / L, women more than 309.39μmol / L, can be diagnosed as hyperuricemia. Gout is caused by purine metabolism or excretion of a group of clinical syndrome, divided into two major categories of primary and secondary, usually from hyperuricemia and informed. Clinical manifestations of acute arthritis, tophi, uric acid kidney stones or renal insufficiency, the performance of the combination of different forms appear.