采用ＶＩＳ×２０／２０型准分子激光仪对１６９例（２８１眼）近视患者进行屈光性角膜切削术（ＰＲＫ）。术前等值球镜屈光度为－１．７５—１６．００Ｄ（－８．１９Ｄ±１．５２Ｄ）。分为两组：Ⅰ组：－１．７５—－６．００Ｄ，１５３眼：Ⅱ组：－６．２５—－１６．００Ｄ，１２８眼。随防一年以上。术后１年实际矫正屈光度在预测矫正度±１．００Ｄ者在Ⅰ、Ⅱ组分别为８７．６％，５４．７％，裸眼视力≥０．５，１．０者在Ⅰ组分别为９７．４％，７４．５％，Ⅱ组分别为８６．７％，３５．９％。并发症主要有角膜上皮下雾状混浊（Ｈａｚｅ），其中Ⅱ组有９．５％的术眼发生了２—３级的Ｈａｚｅ。全组１．９％术眼发生了激素性高眼压 Refractive corneal incision (PRK) was performed on 169 (281 eyes) myopia patients using a VIS × 20/20 excimer laser. Preoperative spherical equivalent refraction was -1.75-16.00D (-8.19D ± 1.52D). Divided into two groups: Ⅰ group: -1.75--6.00D, 153 eyes: Ⅱ group: -6.25--16.00D, 128 eyes. With more than a year. One year after operation, the actual correction of refraction in the predictive degree of correction ± 1.00D in Ⅰ, Ⅱ group were 87.6%, 54.7%, uncorrected visual acuity ≥ 0.5,1.0 in group Ⅰ were 97 .4% and 74.5% in group Ⅱ and 86.7% and 35.9% in group Ⅱ, respectively. The main complications were corneal haze (Haze), in which group Ⅱ, 9.5% of the eyes had grade 2-3 Haze. The entire group of 1.9% ocular hypertension occurred intraocular hypertension