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中国犬数量庞大、经济条件差、群众文化素质低,对犬的大面积强制免疫接种难度很大;由于经济条件和疫苗质量问题,也无法保证人的正规全程的疫苗接种,因此加强犬类动物的管理、发展高质量疫苗并有效应用以及推广暴露前免疫,对控制狂犬病、减少病例起着重大的作用。皮内注射免疫方法可以减少2/3疫苗用量,而且抗体出现的时间早,免疫效果更好,是疫苗免疫领域的一次革命,应大力推广使用。1996年以来我国狂犬病病例已逐年上升,2003年已突破2000例。对造成目前严峻情况的原因分析如下:
Due to the large number of dogs in China, poor economic conditions and low cultural qualities of the masses, it is very difficult to forcibly immunize large dogs in large areas. Due to the economic conditions and the quality of vaccines, formal vaccination of human beings can not be guaranteed. Therefore, Management, development of high-quality vaccines and their effective use and promotion of pre-exposure immunization have played a significant role in the control of rabies and in the reduction of cases. Intradermal injection of immunization methods can reduce the dose of 2/3 vaccine, and antibodies appear early, better immune effect, is a revolution in the field of vaccine immunization, should be vigorously promote the use of. The number of rabies cases in our country has risen year by year since 1996 and exceeded 2000 in 2003. The reasons for the current grim situation are as follows: