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目的:观察益气活血颗粒对大鼠心气虚证CD3+、CD4+、CD8+和cA MP/cG MP(环一磷酸腺苷/环一磷酸鸟苷)的影响。方法:用大鼠负重强迫游泳后通过给予大剂量心得安使大鼠造模定位于心脏,作为心气虚证动物模型。随机分为4组:大、小剂量治疗组(2 g/100 g,0.5 g/100 g益气活血颗粒)、阳性对照组(1 g/100 g天王补心丸)及生理盐水组,均每天1次,连续7 d灌
Objective: To observe the effect of Yiqi Huoxue Granule on the expression of CD3 +, CD4 +, CD8 + and cA MP / cGMP (cyclic adenosine monophosphate / guanosine monophosphate) in rats. Methods: After rats were forced to swim by weight-bearing, the rats were modeled and located in the heart by giving high dose of propranolol as heart-Qi deficiency syndrome animal model. The rats were randomly divided into 4 groups: large and small dose treatment group (2 g / 100 g, 0.5 g / 100 g Yiqi Huoxue granule), positive control group (1 g / 100 g Tiawang Buxin Wan) and saline group 1 day, 7 consecutive days of irrigation