新型隐球菌一般为外源性感染,主要侵犯肺、脑及脑膜,也可侵犯皮肤、骨和关节。对人类而言,该菌通常为条件致病菌。2014年5月9日我院从1例关节外科患者的关节分泌物上涂片检测及培养检测中发现新型隐球菌。1病例介绍患者男,38岁,右小腿反复肿胀疼痛2月,于2014年5月7日入住我院关节外科,经抗炎、抗结核、营养对症支持治疗,指导患者进行肢功能锻炼,12 d后,患者右小腿肿痛 Cryptococcus neoformans is generally exogenous infection, the main violations of the lungs, brain and meninges, but also violations of the skin, bones and joints. For humans, the bacteria are usually pathogenic bacteria. May 9, 2014 In our hospital from 1 case of joint surgery in patients with joint secretions smear detection and detection of C. neoformans. 1 case description Male, 38 years old, right leg pain repeatedly swelling February, on May 7, 2014 admitted to our hospital joint surgery, anti-inflammatory, anti-TB, nutrition symptomatic and supportive treatment, to guide patients with limb function exercises, 12 d, the patient’s right lower leg swelling and pain