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文献报告高血压伴有心绞痛患者,尽管冠脉造影正常,但其冠脉扩张潜力常常受到损害。实验资料表明,心肌内冠脉的结构改变,导致最低冠脉阻力增高和冠脉供血潜力降低。为此,作者作一临床研究。 方法 对象分为两组:(1)原发性高血压组14(男10,女4)例,年龄52±9岁,并因拟诊冠心病作了冠脉造影,结果显示心外膜动脉正常(无一例管腔狭窄>40%),凡有瓣膜性心脏病、扩张型或肥厚型心肌病、浸润性心肌病证据者均予剔除;(2)正常血压组8(男6,
The literature reports that patients with hypertension and angina pectoris often have impaired coronary dilation potential despite normal coronary angiography. Experimental data show that the structural changes of the myocardial coronary artery, resulting in increased minimum coronary resistance and reduced potential for coronary blood supply. To this end, the author made a clinical study. Methods The subjects were divided into two groups: (1) 14 (10 males and 4 females) patients with essential hypertension group aged 52 ± 9 years and coronary angiography due to the proposed diagnosis of coronary heart disease. The results showed that the epicardial arteries Normal (no case of lumen stenosis> 40%), valvular heart disease, dilated or hypertrophic cardiomyopathy, invasive cardiomyopathy were excluded; (2) normal blood pressure group 8 (male 6,