论文部分内容阅读
目的:探讨影响胆管癌切除术后的预后因素。方法:回顾性分析沈阳医学院沈洲医院和中国医科大学附属第一医院1995年1月至2004年12月收治的169例胆管癌的临床资料,并进行多因素Cox回归模型分析。结果:对14个可能影响预后的因素进行分析,单因素分析显示:手术方式、淋巴结转移、残端情况、肿瘤组织类型和远处转移对预后有影响。Cox模型多因素分析显示:手术方式、淋巴结转移和残端情况是影响预后的3个独立的因素,其中手术方式为保护性因素。结论:根治性切除是提高胆管癌远期生存率及改善生活质量的关键,手术方式、淋巴结转移和残端情况是影响胆管癌预后的独立因素。
Objective: To investigate the prognostic factors after cholangiocarcinoma resection. Methods: The clinical data of 169 cases of cholangiocarcinoma admitted to Shenzhou Hospital of Shenyang Medical College and the First Affiliated Hospital of China Medical University from January 1995 to December 2004 were retrospectively analyzed. Multivariate Cox regression analysis was performed. Results: Fourteen factors that may affect the prognosis were analyzed. Univariate analysis showed that surgical modality, lymph node metastasis, stump status, tumor type and distant metastasis had an impact on prognosis. Cox model multivariate analysis showed that: surgical methods, lymph node metastasis and stump are three independent prognostic factors, including surgical methods for the protective factors. Conclusions: Radical resection is the key to improve the long-term survival rate and quality of life of cholangiocarcinoma. Surgical methods, lymph node metastasis and stump status are the independent factors affecting the prognosis of cholangiocarcinoma.