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目的评价18F-FDG PET-CT检查在口腔鳞癌患者的诊断和淋巴结转移灶发现的价值。方法回顾性地分析了18例口腔癌(其中包括16例舌癌和2例口底癌患者)的临床和18F-FDG PET-CT影像学表现及CT平扫的影像学资料。结果(1)原发病灶的发现:全部病例中有5例患者是由PET/CT检查首次发现口腔癌的;PET/CT对原发部位肿瘤病变显示的灵敏度100%(15/15),特异性100%(3/3);CT对原发病灶显示的灵敏度为73.3%(11/15),特异性为66.7%(2/3)。(2)18例口腔癌患者中PET/CT诊断颈部淋巴结转移灶共26个,大小介于0.8~1.5cm之间,标准摄取值(SUV)介于2.5~3.2之间;其中仅有5个淋巴结经病理组织活检证实为淋巴结转移灶。(3)通过PET/CT检查新发现全身其他部位的侵犯和远处转移性病灶8个。结论PET/CT对口腔鳞癌原发灶诊断的灵敏度和特异性均比CT平扫高;全身PET/CT扫描对舌癌和口底癌的临床分期、术后复发的判定更具价值。
Objective To evaluate the value of 18F-FDG PET-CT in diagnosis and lymph node metastasis in patients with oral squamous cell carcinoma. Methods The clinical and imaging features of 18F-FDG PET-CT and CT plain imaging of 18 cases of oral cancer (including 16 cases of tongue cancer and 2 cases of mouth-cancer) were retrospectively analyzed. Results (1) The primary lesion was found: 5 cases of all cases were detected by PET / CT for the first time oral cancer; PET / CT showed 100% (15/15) 100% (3/3). The sensitivity of CT to the primary lesion was 73.3% (11/15) and the specificity was 66.7% (2/3). (2) Twenty-six cervical lymph node metastases were diagnosed by PET / CT in 18 cases of oral cancer patients, ranging in size from 0.8 to 1.5 cm in size and with a standard uptake value (SUV) ranging from 2.5 to 3.2; only 5 A lymph node biopsy confirmed by pathological lymph node metastases. (3) Eight new violations and distant metastatic lesions in other parts of the body were found by PET / CT. Conclusions The sensitivity and specificity of PET / CT in the diagnosis of primary squamous cell carcinoma of oral squamous cell carcinoma are both higher than that of CT. The PET / CT scan is more valuable for clinical diagnosis of tongue carcinoma and oral squamous cell carcinoma.