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对45例肝胆管结石合并肝胆管癌的临床资料进行了回顾性分析,本组结石伴发肝胆管癌的发生率为9.7%。术前确诊率仅为6.7%。45例中高分化腺癌占71.1%,肿瘤位于左、右肝管者占40%。左肝外叶占33.3%。切除肿瘤18例,切除率为40%,平均生存32.4月;姑息性内引流11例,平均生存11.4月;胆道外引流11例,平均生存5.3月。结果表明:结石刺激,继发感染是肝胆管癌发病的重要因素;肝胆管癌切除预后良好,姑息性内引流术的预后明显优于外引流术。
The clinical data of 45 patients with hepatolithiasis associated with hepatocholangiocarcinoma were retrospectively analyzed. The incidence of hepatocholangiocarcinoma in this group was 9.7%. The preoperative diagnosis rate was only 6.7%. Among the 45 cases, 71.1% were well-differentiated adenocarcinomas, and 40% were located in the left and right hepatic ducts. Left hepatic lobe accounted for 33.3%. 18 cases underwent tumor resection. The resection rate was 40%, and the average survival time was 32.4 months. Palliative internal drainage was performed in 11 cases with an average survival of 11.4 months. External biliary drainage was performed in 11 cases with an average survival of 5.3 months. The results showed that: stone stimulation, secondary infection is an important factor in the incidence of hepatobiliary cancer; hepatobiliary cancer resection prognosis is good, the prognosis of palliative internal drainage is significantly better than external drainage.