采用放射免疫分析法测定了40例正常人与99例糖尿病患者血浆内皮素水平。结果显示:糖尿病患者无并发症患者血浆内皮素水平与正常人无显著性差异,但有并发症者显著增高,并随糖尿病病情的加重,病程的延长而依次递增,因此测定内皮素,有助于了解糖尿病患者血管损伤程度,对早期发现其并发症,及判断预后有重要参考价值。 Plasma endothelin levels were measured in 40 normal subjects and 99 diabetic patients by radioimmunoassay. The results showed that there was no significant difference in plasma endothelin level between patients without complications and normal subjects, but there was a significant increase in complication, which was accompanied by the increase of diabetes and the prolonged course of disease. Therefore, the determination of endothelin was helpful To understand the degree of vascular damage in patients with diabetes, early detection of its complications, and prognosis of important reference value.