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农抗101是从制霉菌素产生菌金色链霉菌A-94菌株发酵液中得到的抗真菌油状物。经逆流分溶和分部结晶等方法从农抗101中分到了八个成分,农抗101-己及庚为其中两个成分。经元素分析、紫外光谱、红外光谱、核磁共振及质谱等分析,证明农抗101-己的结构为β-氨甲酰甲基-γ-(2-羟基-3,5-二甲基苯甲酰)-丁内酯;农抗101-庚的结构为β-[(2-羟基-3,5-二甲基苯甲酰)羟甲基]-戊二酰亚胺。
Anti-Fungal 101 is an anti-fungal oil obtained from the nystatin-producing strain S. aureus A-94 fermentation broth. After countercurrent division and fractional crystallization and other methods from the agricultural anti-101 divided into eight components, agricultural anti-101- and G are two of them. The results of elemental analysis, ultraviolet spectrum, infrared spectrum, nuclear magnetic resonance and mass spectrometry showed that the structure of Nongkang 101-hex was β-carbamoyl-γ- (2-hydroxy-3,5-dimethylbenzyl Acyl) -butyrolactone; and the structure of nonglycin 101-g is β - [(2-hydroxy-3,5-dimethylbenzoyl) hydroxymethyl] glutarimide.