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本实验观察了肿瘤坏死因子－α（ＴＮＦ－α）对离体大鼠颗粒细胞孕酮生成的影响和ＴＮＦ－α与ｈＣＧ的关系。发现ＴＮＦ－α可刺激孕酮分泌，且呈显著的时间和剂量依赖关系，ＴＮＦ－α预处理不影响ｈＣＧ对孕酮生成的诱导作用。
This experiment observed the effect of tumor necrosis factor-α (TNF-α) on the progesterone production of isolated rat granulosa cells and the relationship between TNF-α and hCG. TNF-α was found to stimulate progesterone secretion, and showed a significant time-and dose-dependent manner, TNF-α pretreatment does not affect hCG progesterone production induced.