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用单光子吸收法(SPA)测定30例6～32岁神经型地方性克汀病人的前臂骨矿物质含量(g/cm~2)。结果发现克汀病人骨矿含量普遍较低,克汀病组除25岁以上者外其骨矿含量均显著低于正常对照组;克汀组骨矿低下者的检出率男66.6％、女83.3％、儿童100％,同组相应x线骨片骨质疏松的检出率男72. 2％、女83.3％、儿童100％;克汀组平均身高与体重显著低于对照组,但甲状腺功能与正常对照无显著差异。以上结果提示,克汀病人多数有骨质疏松或骨矿低下,后者用SPA容易查出,与x片结果相似,有实用价值。本文讨论了神经型地方性克汀病人骨质疏松的有关因素。
The forearm bone mineral content (g / cm ~ 2) in 30 patients with neurocrine cretinism aged 6 ~ 32 was determined by single photon absorption spectroscopy (SPA). The results showed that the bone mineral content of cretinism was generally low, but the bone mineral content of cretinism group was significantly lower than that of normal control group except for those over 25 years old. The detection rate of bone low in cretinism group was 66.6% male and female 83.3%, children 100%, the same group of x-ray bone osteoporosis detection rate of 72.2% male, 83.3% female, children 100%; cretin group average height and weight were significantly lower than the control group, but the thyroid No significant difference in function and normal control. The above results suggest that the majority of cretinism patients with osteoporosis or bone mineral low, the latter is easy to detect with the SPA, similar results and x, has practical value. This article discusses the factors associated with osteoporosis in patients with neurocrine cretinism.