目的探讨静脉溶栓治疗急性心肌梗死的临床疗效。方法回顾分析80例患者的临床资料。结果溶栓治疗组冠脉再通、心功能改善、严重心律失常及死亡发生率分别为76.12%、89.05%、12.89%、3.85%;常规治疗组冠脉再通、心功能改善、严重心律失常及死亡发生率分别为8.91%、57.62%、34.47%、21.01%。两组比较,差异有统计学意义,P<0.05。结论 AMI患者在休息、吸氧、抗血小板、扩血管药以及肝素抗凝等治疗的基础上,尽早开通梗死相关血管,可缩小梗死面积,保护心功能,降低病死率。 Objective To investigate the clinical efficacy of intravenous thrombolysis in the treatment of acute myocardial infarction. Methods The clinical data of 80 patients were retrospectively analyzed. Results The rate of coronary recanalization, cardiac function improvement, severe arrhythmia and death rate were 76.12%, 89.05%, 12.89% and 3.85% respectively in the thrombolysis group. The recanalization of coronary artery, improvement of cardiac function, severe arrhythmia And the incidence of death were 8.91%, 57.62%, 34.47%, 21.01% respectively. The difference between the two groups was statistically significant, P <0.05. Conclusion Based on the rest of therapy, oxygen inhalation, antiplatelet, vasodilator drugs and heparin anticoagulation therapy, infarct-related blood vessels can be opened as early as possible in patients with AMI, which can reduce infarct size, protect heart function and reduce mortality.