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目的 :应用交感神经皮肤反应检查法 (SSR)定量评价脑梗死患者的交感神经反射活动 ,并探讨其植物神经中枢调节机制。方法 :对 42例急性期脑梗死患者 ,利用肌电图仪刺激双侧正中神经记录SSR ,并以 30例健康人作对照组进行研究。结果 :脑梗死急性期病灶同侧SSR异常 38例 (90 % ) ,对侧为 30例 (71% )。皮层梗死组主要表现为双侧SSR波幅对称性降低 ,与对照组比较差异非常显著 (P <0 0 0 1)。内囊—基底节区梗死组的异常表现形式有SSR缺失 ,双侧波幅降低 (同侧 :P <0 0 0 1,对侧 :P <0 0 1) ,以病灶同侧波幅降低更显著。结论 :SSR可定量评价脑梗死患者的交感神经功能状态 ,对脑梗死患者的植物神经功能障碍有亚临床诊断价值 ;脑梗死急性期可致SSR抑制 ,内囊—基底节区对植物神经系统有重要的调节作用。
Objective: To evaluate the sympathetic reflex activity of patients with cerebral infarction by sympathetic skin reaction test (SSR) and to explore the mechanism of autonomic nerve center regulation. Methods: Forty-two patients with acute cerebral infarction were treated with electromyography to stimulate the bilateral median nerve to record SSR and 30 healthy subjects as control group. Results: In the acute stage of cerebral infarction, 38 cases (90%) had ipsilateral SSR abnormality and 30 cases (71%) contralateral. The main symptom of cortical infarction was the decrease of amplitude symmetry of bilateral SSR, which was significantly different from the control group (P <0.01). The abnormal manifestation of internal capsule-basal ganglia infarction group had SSR deletion and decreased bilateral amplitude (ipsilateral: P <0.01 1, contralateral: P <0.01), and the ipsilateral amplitude decreased more significantly. Conclusion: SSR can quantitatively evaluate the sympathetic functional status of patients with cerebral infarction, and has a subclinical diagnostic value on autonomic dysfunction in patients with cerebral infarction. SSR can be inhibited in the acute phase of cerebral infarction. The effect of internal capsule-basal ganglia on autonomic nervous system Important conditioning.