论文部分内容阅读
目的探讨儿童紫癜性肾炎临床分型与病理分级的关系。方法对98例紫癜性肾炎患儿进行临床分型、病理分级和免疫病理分型,分析其临床分型与病理分级的关系。结果儿童紫癜性肾炎临床以血尿和蛋白尿型多见,其次为肾病综合征型,急进性肾炎型、慢性肾炎型少见;病理分级以Ⅱ~Ⅲ级为主,占75.51%,Ⅳ,Ⅴ和Ⅵ级分别占12.24%,10.21%和2.04%;免疫复合物沉积以IgA+IgG+IgM沉积型多见。结论儿童紫癜性肾炎临床症状严重程度与病理损伤程度基本一致,其中表现为肾病综合征、急进性肾炎和慢性肾炎型者病理改变相对较重。
Objective To investigate the relationship between clinical classification and pathological grade of purpuric nephritis in children. Methods 98 cases of children with purpura nephritis clinical classification, pathological grading and immunopathological classification, analysis of its clinical classification and the relationship between pathological grade. Results The clinical manifestations of purpura nephritis in children were more common in hematuria and proteinuria, followed by nephrotic syndrome, acute nephritis and chronic nephritis. The pathological grades were grade Ⅱ ~ Ⅲ, accounting for 75.51%, Ⅳ, Ⅴ and Ⅵ level accounted for 12.24%, 10.21% and 2.04%, respectively. Immune complex deposition was more common in IgA + IgG + IgM deposits. Conclusions The severity of clinical symptoms of purpuric nephritis in children is basically consistent with the degree of pathological injury. The pathological changes of nephrotic syndrome, acute nephritis and chronic nephritis are relatively severe.