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尽管普遍承认遗传因子在合子、胚胎和胎儿的死亡方面有作用,但在人,除了染色体异常外,却没有鉴定出一种引起胚胎死亡的遗传因子。如以全部妊娠为100%,其中的10~20%因自发流产。头三个月的自发流产中,约60%是由染色体异常引起的。人们把引起自发流产的最重要作用归之于免疫不相容性。然而并不存在表明这一因素意义的直接证据。只有一篇文章,其作者研究了288例自发流产之后,借助免疫荧光研究了流产儿组织的抗原属性。该组18%的
Despite the general recognition that genetic factors have a role in the zygotic, embryonic and fetal deaths, there is no genetic agent that causes embryonic death in humans, except for chromosomal abnormalities. If all pregnancy is 100%, of which 10 to 20% due to spontaneous abortion. About 60% of spontaneous abortions in the first trimester are caused by chromosomal abnormalities. The most important role that causes spontaneous abortion is attributed to immune incompatibility. However, there is no direct evidence of the significance of this factor. Only one article, the authors studied 288 cases of spontaneous abortion, by immunofluorescence study of the antigenic properties of abortion children. The group is 18%