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目的:探索硫酸镁联合拉贝洛尔治疗妊娠期高血压的临床疗效,以期为临床实践提供参考。方法:选取我院于2014年7月至2015年7月间收治的80例妊娠期高血压患者作为临床研究对象,将其随机分为观察组和对照组,每组各40例,给予对照组患者硫酸镁常规治疗,在硫酸镁治疗的基础上给予观察组患者拉贝洛尔联合治疗,对比两组患者治疗前后患者血压变化及其并发症发生情况。结果:经治疗后统计发现,观察组和对照组两组患者治疗前收缩压和舒张压无显著性差异(P>0.05),不具有统计学意义。治疗后观察组收缩压和舒张压明显优于对照组(P<0.05),差异具有统计学意义(P<0.05)。治疗期间观察组出现宫颈裂伤、子宫过度收缩、急产以及产后出血的患者共计9例,占比22.5%,明显优于对照组并发症发病率42.5%(17/40),两组差异显著(P<0.05),具有统计学意义。结论:硫酸镁联合拉贝洛尔在治疗妊娠期高血压疾病方面取得良好的临床应用效果,有效控制患者血压水平,降低临床并发症发病率,提高患者的治疗效果,在临床实践中值得推广应用。
Objective: To explore the clinical efficacy of magnesium sulfate and labetalol in the treatment of gestational hypertension in order to provide reference for clinical practice. Methods: Totally 80 hypertensive patients with gestational hypertension treated in our hospital from July 2014 to July 2015 were selected as clinical study subjects. They were randomly divided into observation group and control group, with 40 cases in each group and control group Patients with magnesium sulfate conventional treatment, magnesium sulfate treatment in the observation group was given the combination of labetalol, compared two groups of patients before and after treatment of blood pressure changes and complications. Results: After treatment, the statistics showed that there was no significant difference in systolic and diastolic blood pressure between the two groups before and after treatment (P> 0.05), which was not statistically significant. After treatment, the systolic and diastolic blood pressure of the observation group was significantly better than that of the control group (P <0.05), the difference was statistically significant (P <0.05). During the treatment period, there were 9 cases of cervical laceration, excessive uterine contraction, emergency labor and postpartum hemorrhage in the observation group, accounting for 22.5%, significantly higher than the incidence of complications in the control group 42.5% (17/40), significant difference between the two groups (P <0.05), with statistical significance. Conclusion: Magnesium sulfate combined with labetalol has good clinical application in the treatment of hypertensive disorder complicating pregnancy. It can effectively control the blood pressure of patients, reduce the incidence of clinical complications and improve the therapeutic effect of patients, which is worthy of popularization and application in clinical practice .