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作者对用伊他康唑(itraconozole)治疗前后花斑癣患处皮屑做了电镜观察。20例患者皮损经Wood 灯检查阳性,真菌镜检阳性,卵圆形糠秕孢子菌培养阳性。每个患者用伊他康唑口服100mg/d,连续5天。治疗开始前,透射电镜可见到大量菌丝型和酵母型糠秕孢子菌存在于所有标本中;角朊细胞内有糠秕孢子菌,主要是菌丝;被感染的角朊细胞的角蛋白被无定形、中等电子密度的物质所代替,经苏丹黑 B 和油红 O 染色证实这种物质为脂质;同
The authors performed electron microscopic observations of danmaic in the area before and after treatment with itraconozole. Twenty patients had positive skin lesions detected by Wood Light, positive fungi and positive Pityrosporum ovale. Each patient was given 100 mg / day of itraconazole orally for 5 consecutive days. Before the start of treatment, a large number of mycelial and yeast-type Pityrosporum spores were found in all specimens by transmission electron microscopy; Pityrosporum spores were found in keratinocytes, mainly mycelium; keratin in infected keratinocytes was amorphous , Medium electron density material replaced by Sudan black B and oil red O staining confirmed this substance as lipid;