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少突胶质细胞(oligodendroglia)的存在及其功能的发挥是髓鞘非依赖性的,如果少突胶质细胞的功能发生障碍,将在许多相关疾病中导致轴突变性。引起变性的原因目前还未确定,有学者认为可能是能量代谢物的缺乏所引起的,例如葡萄糖、乳酸盐等。
The presence and function of oligodendroglia is myelin-independent and if oligodendrocytes function impaired, they lead to axonal degeneration in many related diseases. The cause of denaturation has not yet been determined, some scholars think it may be the lack of energy metabolites caused, such as glucose, lactate and so on.