临床上常用的胆碱脂酶复能剂有解磷啶(pAm-Ⅰ)、氯磷啶(PAM-Cl)及双复磷(DMO_4)。其机制主要通过化学竞争,夺取磷酰化胆碱脂酶分子中的磷酰基,使被有机磷抑制的胆碱脂酶重新恢复活性;同时还可直接作用于有机磷,解除所致烟碱样毒作用。促进中枢苏醒。为此,有的则不加分析的大量使用,甚至滥用,造成胆碱脂酶复 Clinician commonly used cholinesterase agents are phosphorylated pyridine (pAm-Ⅰ), chlorine and phosphorus (PAM-Cl) and double complex phosphorus (DMO_4). The mechanism mainly through chemical competition, to capture phosphoryl choline phosphoryl choline lipase molecules, so that organic phosphorus inhibition of cholinesterase activity restored; the same time, can also be directly on the organic phosphorus, the lifting of nicotine-induced Toxic effects. Promote the central awakening. For this reason, some are not used extensively or even abused, resulting in cholinesterase complex