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用放射免疫分析方法检测40例尿毒症患者血液透析(HD)前后血浆降钙素基因相关肽(CGRP)水平,发现HD前后血浆CGRP均明显高于正常对照组(P<0.001),HD后较HD前明显降低(P<0.01),CGRP与血肌酐(Scr)呈显著正相关(r=0.7426)。提示CGRP变化与肾功能损害程度有关。
The levels of plasma calcitonin gene related peptide (CGRP) before and after hemodialysis (HD) were determined by radioimmunoassay in 40 patients with uremia. The plasma CGRP level before and after HD was significantly higher than that of the normal control group (P <0.001) HD was significantly lower (P <0.01), CGRP was positively correlated with serum creatinine (Scr) (r = 0.7426). Tip CGRP changes and the degree of renal dysfunction.