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本文测定了38例脑血管病患者和26例正常人血清及红细胞膜SA含量。结果:脑血管病患者血清TSA含量明显高于对照组(P<0.01),红细胞膜SA含量明显低于对照组(P<0.05),且出血量及梗塞灶大小与血清TSA呈正相关(P<0.05),与红细胞膜SA含量呈负相关(P<0.01)。恢复期患者的血清TSA显著低于急性期(P<0.05),其红细胞膜SA含量极显著高于急性期患者(P<0.01)。而脑出血与脑梗塞及其不同年龄,性别组间血清和红细胞膜SA含量均无显著性差异(P均>0.05)。提示脑血管病患者血清及红细胞膜SA含量变化,可以反映脑血管病患者脑损伤的程度,对指导治疗、判定预后具有一定的参考意义。
This article measured 38 patients with cerebrovascular disease and 26 normal subjects serum and erythrocyte membrane SA content. Results: Serum TSA levels in patients with cerebrovascular disease were significantly higher than those in the control group (P <0.01). SA content in the erythrocyte membrane was significantly lower than that in the control group (P <0.05), and the amount of bleeding and infarct size were positively correlated with serum TSA (P <0.05), but negatively correlated with SA content of erythrocyte membrane (P <0.01). The serum TSA of convalescent patients was significantly lower than that of acute phase (P <0.05), and the SA content of erythrocyte membrane was significantly higher than that of acute phase (P <0.01). There was no significant difference in the content of SA in serum and erythrocyte membrane between cerebral hemorrhage and cerebral infarction and their different age and gender groups (all P> 0.05). These results suggest that the change of SA content in serum and erythrocyte membrane in patients with cerebrovascular disease can reflect the degree of brain injury in patients with cerebrovascular disease and have certain reference value for guiding treatment and prognosis.