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为建立我国北方农村中等经济收入地区乙型病毒性肝炎 (乙肝 )免疫预防的模式 ,在山东省部分农村进行了乙肝疫苗免疫效果观察。对 15 18名孕妇进行了产前筛检 ,对 2 10 4名新生儿按母亲筛检结果分组并按不同模式免疫 ,于免疫后 1年采血监测乙肝免疫学指标 (HBsAg ,抗 -HBs,抗 -HBc)。结果表明 ,所有新生儿抗 -HBs阳性率均在 89 5 %以上 ;筛检和未筛检孕妇所产新生儿抗 -HBs阳性率之间无显著的统计学意义 ;两种免疫方式免疫后 1年抗 -HBs阳性率之间无显著的统计学意义
In order to establish a mode of immunization prevention of hepatitis B virus (HBV) in rural middle-income areas in northern China, the effect of hepatitis B vaccine was observed in some rural areas of Shandong Province. A total of 15 18 pregnant women underwent prenatal screening. Groups of 2 10 4 newborns were grouped according to their mother’s screening results and immunized according to different modes. Blood samples were collected 1 year after immunization to monitor the immunological indicators (HBsAg, anti-HBs, anti-HBs -HBc). The results showed that the positive rate of anti-HBs in all newborns was above 89.5%; there was no statistically significant difference between the positive rate of anti-HBs in neonates born in screening and non-screening pregnant women; The anti-HBs positive rate in the year was not statistically significant