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全身性红斑狼疮Systemic Lupus Erythematosis(简称SLE),过去一直被认为是一种原因不明的胶原性疾病,其临床病死率颇高(急性期病死率高达50%以上)。最近日本学者对SLE病因与狼疮性肾炎发病机理进行了探讨。冈山大学医学部第三内科仓田、典之等于1978年报告他们对141例SLE病人身上获得的219份肾组织标本,用萤光抗体法检查,68例病人进行了肾炎方面的检查,其中10例做了解剖,从肾脏里分离出各种的抗核抗体。据萤光检查结果,狼疮性肾炎病理变化分五个类型;线型、肾小球膜型、膜型、粒状型、块型。它们的分类比例为:线型占18%,
Systemic Lupus Erythematosis (SLE), a systemic lupus erythematosus, has historically been considered as an unexplained collagen disease with a high case-fatality rate (up to 50% in acute cases). Recently, Japanese scholars have discussed the pathogenesis of SLE and lupus nephritis. Okayama University School of Medicine Department of Internal Medicine Kurada, Code equal to 1978 report on their 141 cases of SLE patients obtained 219 specimens of kidney tissue, using fluorescent antibody test, 68 patients were nephritis examination, of which 10 patients Anatomy, isolated from the kidneys in a variety of anti-nuclear antibodies. According to the results of fluorescent examination, lupus nephritis pathological changes in five types; linear, mesangial, membranous, granular, block type. Their classification ratio is: linear accounted for 18%