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目的了解子宫切除手术围手术期抗菌药物使用并评价其合理性。方法随机抽取医院2009年7月-2010年6月90份子宫切除术患者病历,对其围手术期抗菌药物的使用进行回顾性调查。结果围手术期抗菌药物使用率为100.00%,共涉及6大类16种抗菌药物,使用频率最高的是青霉素类73.33%、其次是硝基咪唑类和头孢菌素类分别为55.56%、28.89%,抗菌药物联用率为48.89%,首次用药时间在术前<2 h为44.45%,术后用药时间<72 h为6.67%。结论围手术期抗菌药物使用存在一定程度的不合理现象,有待于进一步加强围手术期抗菌药物应用管理,提高规范的围手术期抗菌药物使用率,尽量缩短术后预防性抗菌药物使用时间。
Objective To understand the perioperative antimicrobial use of hysterectomy and to evaluate its rationality. Methods A total of 90 cases of hysterectomy patients in hospital from July 2009 to June 2010 were randomly selected and their perioperative antibacterials were retrospectively reviewed. Results The perioperative antibacterials utilization rate was 100.00%, involving 6 kinds of 16 kinds of antibacterial drugs, the highest frequency of use was penicillins 73.33%, followed by nitroimidazoles and cephalosporins were 55.56%, 28.89% , The combined use of antibacterials was 48.89%, the first time of medication was 44.45% in <2 h before operation and 6.67% in <72 h after operation. Conclusions Perioperative antimicrobial use has a certain degree of unreasonableness. It is necessary to further strengthen the perioperative management of antimicrobial agents, to improve the standard of perioperative antibacterials utilization, and to shorten the postoperative period of preventive antimicrobial agents.