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系膜 IgA 肾小球肾炎(IgA-GN)是成年人肾小球疾病中最常见的类型,但表现为肾病综合征较少,其发病率为5~10%之间,常见于肾小球硬化或严重增殖性病变如新月体。本文报道1例对皮质激素敏感的肾病综合征伴系膜 IgA—GN。病例:男性,17岁,因踝部和眼睑浮肿3天入院,主诉腹痛和2天内体重增加4kg,以往无浮肿、蛋白尿,高血压史,也无关节痛、皮疹和腹泻史,体检血压110/70mmHg,除眼睑及踝部浮肿外其它无特殊。实验室检查 ESR83mm/h,中度低蛋白血症(4.8g/d1)伴低白蛋白血症(2.4g/d1)和血胆固醇
Mesangial IgA Glomerulonephritis (IgA-GN) is the most common type of glomerular disease in adults, but exhibits less nephrotic syndrome with a prevalence of 5 to 10%, commonly found in glomeruli Sclerosis or severe proliferative lesions such as crescent. This article reports 1 case of corticosteroid-sensitive nephrotic syndrome with mesangial IgA-GN. Case: Male, 17 years old, admitted to hospital due to ankle and eyelid edema for 3 days, complained of abdominal pain and body weight gain within 2 days 4kg, no history of edema, proteinuria, history of hypertension and no history of joint pain, skin rash and diarrhea. Physical examination Blood pressure 110 / 70mmHg, in addition to eyelid and ankle swelling other no special. Laboratory tests ESR83mm / h, moderate hypoproteinemia (4.8g / d1) with hypoalbuminemia (2.4g / d1) and blood cholesterol