脑组织本身无贮氧和贮能功能,完全依赖于血液供给氧气和葡萄糖进行代谢提供能量而发挥功能.一旦阻断血液循环,能量代谢立即发生紊乱,并出现脑机能障碍.近年来的研究发现,脑缺血后,除能量代谢发生异常外,脑组织中单胺类神经介质的代谢亦发生障碍.有人研究发现,一过性脑血缺后,虽然能量代谢很快恢复,但是单胺的紊乱仍然持续下去.有人认为,缺血后脑组织中单胺类神经介质的变化与缺血后脑损伤的发生关系密切.因此,研究缺血性脑组织单胺类神经介质的变化规律,对防治脑缺血和缺血性脑血管病具有重要意义.本文 Brain tissue itself has no oxygen storage and storage function, relying solely on the blood supply of oxygen and glucose metabolism to provide energy and function.Once the blood circulation, energy metabolism immediately disorder, and brain dysfunction.Recent studies have found , Cerebral ischemia, in addition to abnormal energy metabolism, brain tissue monoamine neurotransmitter metabolism also obstacles.It was found that transient cerebral blood deficiency, although the rapid recovery of energy metabolism, but the monoamine It is believed that the changes of monoamine neurotransmitters in the brain tissue after ischemia are closely related to the occurrence of ischemic brain injury.Therefore, to study the changes of monoamine neurotransmitters in ischemic brain tissue, Ischemic and ischemic cerebrovascular disease is of great importance