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目的:观察益气活血中药对慢性心衰气虚血瘀水停型患者的临床疗效及远期预后的影响。方法:选择80例慢性心衰属气虚血瘀水停型患者,随机分为治疗组和对照组,两组均给予基础西药治疗,治疗组在基础西药治疗的基础上加服益气活血中药颗粒剂,疗程1个月,随访9个月,治疗前后分别记录患者心衰疗效(Lee氏)记分、心功能分级(NYHA)、中医症状疗效积分、6 min步行试验、生活质量调查表评分、氢氯噻嗪片停减率、再住院率等指标。记录患者治疗前后血、尿常规、肝功能(AST、ALT)、肾功(CR、BUN)等指标。结果:治疗前后两组患者心功能分级、心衰疗效积分,均较前改善(P<0.05);中医症状疗效积分、6 min步行试验、生活质量调查表评分、氢氯噻嗪片停减率、再住院率较治疗前比较均明显改善,且治疗组优于对照组(P<0.05)。结论:益气活血中药可明显改善CHF患者心功能分级,提高心衰疗效,改善临床症状,增加患者运动耐量,提高生活质量,减少氢氯噻嗪使用量,降低其再住院率。
Objective: To observe the effect of Yiqi Huoxue Chinese medicine on the clinical curative effect and long-term prognosis of patients with chronic heart failure with deficiency of qi and blood stasis. Methods: Eighty chronic heart failure patients were randomly divided into treatment group and control group. Both groups were given basic western medicine. On the basis of western medicine treatment, the treatment group was given Yiqi Huoxue Chinese medicine granules The patients were followed up for 9 months. The Lee’s score, NYHA, TCM symptom score, 6-min walk test, quality of life questionnaire, hydrochlorothiazide Film reduction rate, re-hospitalization rate and other indicators. Record before and after treatment of patients with blood, urine, liver function (AST, ALT), renal function (CR, BUN) and other indicators. Results: Before and after treatment, the scores of heart function and heart failure were both improved (P <0.05); symptom score of TCM, 6 min walk test, quality of life questionnaire, withdrawal rate of hydrochlorothiazide, rehospitalization Compared with the control group, the treatment group was significantly better than the control group (P <0.05). Conclusion: Yiqi Huoxue Chinese medicine can significantly improve the classification of heart function in patients with CHF, improve the efficacy of heart failure, improve clinical symptoms, increase exercise tolerance, improve quality of life, reduce the use of hydrochlorothiazide and reduce its rehospitalization rate.