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合成了N-烷基-N-磷酰基甘氨酸衍生物。在Lewis酸催化下成功地进行Freidel-Crafts反应,得到分子内环化产物苯并-3-氮杂环庚酮-[1]衍生物,并在温和条件下脱保护基。
N-alkyl-N-phosphorylglycine derivatives were synthesized. The Freidel-Crafts reaction was successfully carried out under Lewis acid catalysis to obtain the benzo-3-azacycloheptan- [1] derivative, which is an intramolecular cyclization product, and the deprotection was carried out under mild conditions.