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观察胆脂瘤型中耳炎患者在术中用泰利必妥（氧氟沙星）滴耳剂治疗感染性病灶的临床效果及安全性。方法：将胆脂瘤型中耳炎病例随机分为两组：泰利必妥组２３例，硼酸组１９例。所有患者均行开放式鼓室成形术，并分别用０．３％泰利必妥和４％硼酸行术腔浸泡冲洗。结果：临床治愈率分别为８２．６％、５０．０％，两组差异显著（Ｐ＜０．０５），治疗中未发现副作用。结论：手术中用泰利必妥滴耳剂可以提高手术效果，且具有较高的安全性。
To observe the clinical effect and safety of patients with cholesteatoma otitis media treated with telbivudine (ofloxacin) ear drops in the treatment of infectious lesions. Methods: The cases of cholesteatoma otitis media were randomly divided into two groups: 23 cases in telbital group and 19 cases in boric acid group. All patients underwent open tympanoplasty with 0.3% telbivudine and 4% boric acid respectively. Results: The clinical cure rates were 82.6% and 50.0%, respectively, with significant difference between the two groups (P <0.05). No side effects were found during the treatment. Conclusion: The use of telomethalc eardrops during operation can improve the operation effect and have higher safety.