论文部分内容阅读
生胃酮(Carbenoxolone 或Biogastrone)是治疗消化性溃疡病的新药、系甘草次酸(Glycycrrhetinic acid)的水溶性衍生物—3-β—甘草次酸琥珀酸单酯的双钠盐。1962年首先在英国由Doll 报道了生胃酮临床试用资料。1972年美国开始临床试用生胃酮,其结果与Doll 的报道相似。
Carbenoxolone or Biogastrone is a new drug for the treatment of peptic ulcer disease and is a bis-sodium salt of -3-β-glycyrrhetinosuccinate, a water-soluble derivative of glycyrrhetinic acid. In 1962 first reported in the United Kingdom by the Doll stomach ketone clinical trial data. In 1972, the United States began clinical trials of endosulfan, the results of which are similar to those reported by Doll.