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弥漫性甲状腺肿甲亢(Graves 病)是由甲状腺刺激抗体(TSAb)作用于甲状腺细胞膜上 TSH 受体引起的。所有患者均有易测出的 TSAb。甲状腺部分切除后,抗体滴度通常即下降,病人症状得到持久缓解。这一现象至今仍难解释。
Graves’ disease is caused by the thyroid stimulating antibody (TSAb) acting on the thyroid cell membrane TSH receptors. All patients had a readily detectable TSAb. After partial thyroidectomy, antibody titers usually fall, and patient symptoms are permanently relieved. This phenomenon is still difficult to explain.