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近年来由于工业生产的发展,新化学物质不断出现,化学代用品大量增加,人类除参加生产直接接触化学物质,也在生活上接触大量医药、农药、食品添加剂、防腐剂等化学物质,同时环境也正受到这些物质的严重污染,从各方面造成健康上的威胁。最近研究揭示了化学物质致癌和致突变有明显巧合,这使化学物质不仅对现存者有引起恶变的可能,还会造成对子孙后代的危害。于是在人类环境中化学致突变物遗传损害方面的研究引起很大的注意,从防癌、防畸、防突变出发,要求用快速检测方法以识别潜在危害,检出与人有关的致突变活性物质,并对这些物质严加控制。目前已发展了不少快速筛选方法,但各具优缺
In recent years, due to the development of industrial production, new chemical substances are constantly appearing and chemical substitutes are greatly increased. In addition to participating in direct contact with chemicals, human beings also come into contact with a large amount of chemicals such as medicine, pesticides, food additives and preservatives in their daily lives. At the same time, They are also seriously polluted by these substances and pose a health threat in all aspects. Recent research has revealed that there is a clear coincidence between the carcinogenicity and the mutagenicity of chemical substances, which makes the chemical substances not only have the potential to cause malignant transformation to the existing ones, but also cause harm to future generations. Therefore, studies on the genetic damage caused by chemical mutagens in the human environment have drawn great attention. In terms of anti-cancer, anti-teratogenicity and anti-mutation, rapid detection methods are required to identify potential hazards and detect human-related mutagenic activity Material, and strict control of these substances. There have been many rapid screening methods developed, but each has its own advantages and disadvantages