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目的:探索健康女性月经周期不同时相性激素的变化趋势及其与精神质因子的相关性。方法:选取月经周期规律的健康女性80例,在入组时填写艾森克人格简式量表(EPQ-RSC),并计算该量表各个维度的评分,即神经质、精神质、内外向及可信度。依据常模将其分为高低精神质组,连续3个月经周期在其卵泡早期、卵泡晚期、黄体中晚期抽取空腹血样检测其性激素6项指标,即雌二醇(E2)、卵泡刺激素(FSH)、促黄体生成素(LH)、泌乳素(PRL)、孕酮(Prog)、睾酮(T)。结果:高精神质组的FSH在卵泡早期、卵泡晚期、黄体中晚期较低精神质组高;且LH在卵泡早期、黄体中晚期高精神质组较高(P<0.05)。而T在黄体中晚期高精神质组则较低(P<0.05)。结论:精神质因子评分可能影响健康女性激素水平的变化。
Objective: To explore the change tendency of sex hormones in healthy women at different phases of menstrual cycle and its correlation with psychotic factors. Methods: Eighty healthy women with regular menstrual cycle were enrolled. The EPQ-RSC scale was included in the questionnaire, and scores of all dimensions of the scale were calculated, namely neuroticism, psychoticism, extroversion and extroversion Credibility. According to the norm group, the rats were divided into high and low group according to the normotensive group. Six fasting blood samples were taken from the early menstrual follicles, the late follicles and the late mid luteal phase for 3 consecutive menstrual cycles to detect the sex hormones including estradiol (E2), follicle-stimulating hormone FSH), luteinizing hormone (LH), prolactin (PRL), progesterone (Prog), testosterone (T). Results: In the early stage of follicular, late stage of follicular and late stage of corpus luteum, FSH of high group was higher than that of high group. While T was lower in the middle and late prolactin group (P <0.05). Conclusion: The psychotic factor score may affect the changes of hormone levels in healthy women.