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目的:分析2型糖尿病合并败血症患者的临床特点以及耐药菌分布情况,提高对糖尿病合并败血症的早期诊断率以及合理选用抗生素。方法:对2008年1月～2010年10月在我院内分泌科住院的2型糖尿病并发败血症患者临床资料进行回顾与分析。结果:HbA1C>7%组患者糖尿病慢性并发症、高血糖、酮症酸中毒以及多器官功能衰竭明显多于血糖控制组,统计学有明显的差异(P<0.05);HbA1C≤7%组培养出的菌株对药物的敏感性均高于HbA1C>7%组培养出的菌株。但所有菌株对阿莫西林、哌拉西林和复方新诺明均不敏感。结论:长期的血糖控制水平对糖尿病合并败血症患者的预后有着明显的影响。
Objective: To analyze the clinical features and the distribution of drug-resistant bacteria in patients with type 2 diabetes mellitus and sepsis and improve the early diagnosis rate of diabetes mellitus septicemia and rational use of antibiotics. Methods: The clinical data of patients with type 2 diabetes mellitus and sepsis hospitalized in Department of Endocrinology in our hospital from January 2008 to October 2010 were reviewed and analyzed. Results: The chronic complications of diabetes, hyperglycemia, ketoacidosis and multiple organ failure in HbA1C> 7% group were significantly more than those in control group (P <0.05); HbA1C≤7% Out of the strains of the drug sensitivity were higher than the HbA1C> 7% group of strains cultured. However, all strains were not sensitive to amoxicillin, piperacillin and cotrimoxazole. CONCLUSIONS: Long-term glycemic control has a significant effect on the prognosis of patients with diabetes mellitus and septicemia.