丹皮酚(Paeonol)又称牡丹酚(2-羟基-4-甲氧基乙酰苯,C_9H_(10)O_3),是良好的解热镇痛药。但其在水中的溶解度很差,配制时需加入大量的吐温80助溶。而且制剂色泽不佳,在实验中我们主要就色泽问题进行了探讨,以440nm处吸收值作为色泽优劣的衡量值,运用正交设计法对注射液配方进行了筛选。 Paeonol, also known as Paeonol (2-hydroxy-4-methoxyacetophenone, C_9H_ (10) O_3), is a good antipyretic analgesic. However, its solubility in water is poor, when formulated by adding a large amount of Tween 80 soluble. And the preparation of poor color, in the experiment we mainly on the issue of color to explore the absorption value of 440nm as a measure of the pros and cons of color, the use of orthogonal design of the injection formulations were screened.