目的　探讨用胶原管 (collagentube)架桥于脊髓前角与撕脱的脊神经根间 ,促使轴突再生长 ,以修复脊髓到周围神经的传导通道。方法　用大白鼠制成臂丛损伤模型 ,分为四组。A组用胶原管架桥连接脊髓前角与撕脱的神经根 ;B组把自体坐骨神经分支移植物放入到连接于脊髓前角与神经根的胶原管内 ;C组用一段周围神经移植物架桥在脊髓与撕脱的神经根之间 ;D组为仅作神经根撕脱的对照。结果　采用电生理学监测修复后肌肉的电生理活动及收缩功能 ,通过病理学及组化学 ,观察脊髓和神经元的轴突再生状况并作了移植物的形态学分析 ,证明大量的新生神经纤维经过移植物进入到被修复的神经根及其周围神经 ,并使神经组织和肌肉重新形成了运动终板 ,从而恢复了一定的肌肉收缩功能。结论　用胶原管架桥作CNS到PNS神经再连接 ,是在神经移植实验中可促使轴突再生长的有效方法 OBJECTIVE: To investigate the relationship between the spinal cord roots and the anterior horn of the spinal cord and the avulsion of the spinal nerve roots by collagenase collagens to promote axonal regrowth and to repair the conduction path from the spinal cord to the peripheral nerves. Methods Brachial plexus injury models were made in rats and divided into four groups. In Group A, the autonomic sciatic nerve branch graft was placed in the collagen tube connected to the anterior horn of the spinal cord and the nerve root. In Group C, a section of peripheral nerve graft Bridge between the spinal cord and avulsion of nerve roots; D group only for nerve root avulsion control. Results Electrophysiology was used to monitor the electrophysiological activity and contractile function of the repaired muscle. Morphology and histochemistry were used to observe the axonal regeneration status of the spinal cord and neurons. Morphological analysis of the grafts showed that a large number of nasal nerve fibers passed The graft enters the repaired nerve root and its peripheral nerves and regenerates the motor end plates of the nerve tissue and muscles, thereby restoring certain muscle contractile functions. Conclusion Collagen tube bridging for CNS to PNS nerve reconnection is an effective method to promote axonal regrowth in nerve grafting experiment