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目的:探讨食管碘染色在食管癌前病变及早期食管癌诊治中的应用价值。方法:在2011年1月至2013年1月间对我科胃镜检查肉眼疑似微小和浅表粘膜病变者行食管碘染,阳性者行多点活检。结果:560例疑食管粘膜病变者碘染后有414例不染或浅染,碘染阳性者活检病理诊断食管癌25例、早癌10例、重度不典型增生63例、中度不典型增生31例、轻度不典型增生23例、炎症96例,检出率分别为6%、2.4%、15.2%、7.5%、5.6%、23.2%。23例碘染确定切除范围后行粘膜切除术患者,标本边缘均无病变累及。结论:食管碘染能提食管高早癌及癌前病变的诊断率,并可为内镜下食管粘膜切除及进展期食管癌外科切除确定手术范围提供参考,该方法值得在临床推广应用。
Objective: To investigate the value of esophageal iodine staining in the diagnosis and treatment of esophageal precancerous lesions and early esophageal cancer. Methods: From January 2011 to January 2013, we performed multi-point biopsy on mycology gastroscopy in patients with suspicious microscopic and superficial mucosal lesions under esophageal iodine staining. Results: Of the 560 cases suspected of esophageal mucosal lesions, there were 414 cases of non-staining or light stain after iodine staining, 25 cases of esophageal cancer with iodine-staining, 10 cases of early cancer, 63 cases of severe atypical hyperplasia and moderate dysplasia 31 cases, mild dysplasia in 23 cases and inflammation in 96 cases. The detection rates were 6%, 2.4%, 15.2%, 7.5%, 5.6% and 23.2% respectively. 23 cases of iodine staining to determine the resection of the mucosal resection patients, no edge lesions involved. Conclusion: Esophageal iodine dye can improve the diagnosis rate of esophageal cancer and precancerous lesions, and provide a reference for surgical resection of esophageal mucosal resection and esophageal carcinoma under endoscopy. This method is worthy of clinical application.