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为了探讨肝组织中ＨＣＶＲＮＡ的意义，使用原位ＰＣＲ检测技术，对２６例血清ＨＣＶ标志物阳性肝病者进行检测。结果显示该方法特异性强，肝组织ＨＣＶＲＮＡ阳性率为６９２％，阳性信号主要定位在细胞浆，个别呈浆核型，但仍以浆型为主。肝功损害与肝细胞中ＨＣＶＲＮＡ有一定相关性。
In order to investigate the significance of HCVRNA in liver tissue, 26 cases of HCV positive liver disease were detected by in situ PCR. The results showed that the method was specific and the positive rate of HCV RNA in liver tissue was 692%. The positive signal was mainly located in the cytoplasm, and some of the positive cells were plasmacytoid type. Hepatic damage and HCVRNA in liver cells have a certain relevance.