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目的 观察评价内镜下局部注射肾上腺素与高渗氯化钠混合液治疗非门脉高压性上消化道出血的疗效。方法 符合入选条件的 6 4例上消化道出血患者随机分组 ,内镜治疗组 4 3例 ,局部注射肾上腺素 +高渗氯化钠溶液 ;常规内科治疗组2 1例 ,禁食、静注洛赛克、止血剂等常规保守治疗。结果 内镜治疗组与常规内科治疗组的住院时间、住院费用、输血量、急诊手术率、3个月未愈率分别为 4 .2± 1.7d、8.5± 2 .3d(P <0 .0 1) ,987.5± 2 15 .3元、6 315 6 .6± 4 17.4元 (P <0 .0 1) ,2 .4 3± 1.5 5U、3 36± 1.6 8U(P <0 .0 5 ) ,2 .33%、14 .2 8% (P <0 .0 5 ) ,6 .9%、9.5 % (P >0 .0 5 )。结论 内镜治疗组与内科常规治疗组相比较 ,明显缩短住院时间 ,降低住院费用 ,减少输血量 ,降低急诊手术率 ,近期治疗效果无显著差异。
Objective To evaluate the efficacy of endoscopic injection of epinephrine and hypertonic sodium chloride in the treatment of non-portal hypertensive upper gastrointestinal bleeding. Methods Sixty-four patients with upper gastrointestinal bleeding who met the inclusion criteria were randomly divided into 4 groups: endoscopic treatment group, local injection of epinephrine + sodium chloride solution; routine medical treatment group, 21 cases, fasting, intravenous injection Saikai, hemostatic agents and other conventional conservative treatment. Results The length of hospital stay, hospitalization cost, blood transfusion and emergency operation rate in endoscopic treatment group and conventional medical treatment group were 4.2 ± 1.7 days and 8.5 ± 2.3 days (P <0. 1), 987.5 ± 2 15.3 yuan, 6 315 6 .6 ± 4 17.4 yuan (P <0.01), 2.3 ± 1.5 5U, 3 36 ± 1.6 8U (P <0.05) , 2.33%, 14.28% (P <0.05), 6.9%, 9.5% (P> 0.05), respectively. Conclusion Compared with the conventional treatment group, the endoscopic treatment group significantly shortened the hospital stay, reduced hospitalization costs, reduced blood transfusion, and reduced the emergency operation rate. There was no significant difference in the short-term treatment effect between the two groups.