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目的:观察来曲唑联合复方玄驹胶囊促排卵治疗不孕症的效果。方法:研究对象来自我院2015年11月-2016年11月收治的120例不孕症患者。将120例患者随机分为两组,一组进行研究(治疗组),另一组进行对比(对照组),每组各60例,对照组患者采用来曲唑进行治疗,治疗组在对照组治疗的基础上给予复方玄驹胶囊。比较两组不孕症患者人绒毛膜促性腺激素(hCG)日子宫内膜厚度、血清雌二醇(E_2)、黄体生成素(LH)水平、黄体中期孕酮(P)水平、优势卵泡直径和数目、周期妊娠率。结果:治疗组hCG日子宫内膜厚度、E_2、LH水平、黄体中期P水平均高于对照组,且优势卵泡直径和个数、总妊娠率较对照组均明显升高,两组不孕症患者差异具有显著性,存在统计学意义(P<0.05)。结论:对不孕症患者应用来曲唑联合复方玄驹胶囊进行治疗效果确切,可以明显改善不孕患者子宫内膜厚度,提高患者hCG日LH水平、E_2水平和黄体中期P水平,增加成熟卵泡的个数和直径,提高不孕症患者的妊娠率,值得临床上推广应用。
Objective: To observe the effect of letrozole combined with Xuanju Capsule in treating infertility. Methods: The subjects were from 120 infertility patients who were admitted to our hospital from November 2015 to November 2016. One hundred and twenty patients were randomly divided into two groups: one group (treatment group), the other group (control group), 60 cases in each group, and the control group were treated with letrozole. The treatment group in the control group On the basis of treatment given Compound Xuan Ju Capsule. The endometrial thickness, serum estradiol (E2), luteinizing hormone (LH) level, progesterone (P) level in mid luteal phase and the dominant follicle diameter of hCG were compared between two groups And the number of cycles pregnancy rate. Results: The endometrial thickness, E_2 and LH levels and the mid-luteal P level in the treatment group were higher than those in the control group, and the diameter and number of dominant follicles and the total pregnancy rate were significantly higher than those in the control group There was significant difference in patients with statistical significance (P <0.05). Conclusion: The application of letrozole combined with Xuanju capsule in patients with infertility treatment is effective, can significantly improve the endometrial thickness of infertility patients, improve the level of LH in patients with hCG, E_2 levels and mid-luteal P level, increase the mature follicles The number and diameter, improve the pregnancy rate of infertility patients, it is worth promoting the clinical application.