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组织胺球蛋白是一种由丙种球蛋白与磷酸组织胺合成的抗组织胺的抗原性制剂。它可使患者升高组织胺固定指数(HistaminofixicIndex),从而获得抗组织胺的免疫性。有人认为组织胺球蛋白可增加组织胺酶,并使其活性加强,而导致组织胺作用减弱。业已发现过敏性疾病患者的抗组织胺因子常减低或完全缺如,经组织胺球蛋白治疗后在临床症状好转的同时,抗组织胺因子凝集滴度有明显升高的现象。我们于1977年利用除菌滤板上遗弃的丙球试制组织胺球蛋白十余批。经鉴定合格后,用于治疗过敏性哮喘,取得了较满意的效果。制备一、取注射用硫代硫酸钠9.6克于无菌干燥1000毫升烧杯内,加无热原蒸馏水600毫升使之溶解,再加入1.5毫克注射用磷酸组织胺混匀。二、待制备人血丙种球蛋白除菌过滤完后
Histamine Globin is an antihistamine antihistamine synthesized from gamma globulin and histamine phosphate. It allows patients to raise the Histaminofixic Index to obtain anti-histamine immunity. Some people think that histamine amylin can increase histamine enzyme, and to enhance its activity, resulting in reduced histamine effect. Histamine has been found in patients with allergic disease often reduced or completely lack of anti-histamine factor, histamine amidoglobin treatment improved clinical symptoms at the same time, anti-histamine factor agglutination titers were significantly higher phenomenon. In 1977, we made more than ten batches of histamine globulin by using the abandoned balls on the filter board. After the identification of qualified, for the treatment of allergic asthma, and achieved more satisfactory results. Preparation of a take injection of 9.6 grams of sodium thiosulfate in a sterile 1000 ml beaker dry, add pyrogen-free distilled water 600 ml to dissolve, then add 1.5 mg injection of histamine phosphate mix. Second, to be prepared after blood gamma globulin sterile filtration