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目的:探讨奥美拉唑治疗消化性溃疡的临床疗效。方法:将56例消化性溃疡患者随机分为治疗组和对照组各28例,治疗组给予奥美拉唑进行治疗,对照组给予法莫替丁进行治疗。结果:治疗组有效率为96.4%,对照组有效率为71.4%,两者有效率比较差异有统计学意义(P<0.05)。治疗组不良反应发生率为7.2%,对照组为32.1%,两组比较差异具有统计学意义(P<0.05)。结论:奥美拉唑治疗消化性溃疡疗效好,不良反应少,值得临床推广。
Objective: To investigate the clinical efficacy of omeprazole in the treatment of peptic ulcer. Methods: Fifty-six patients with peptic ulcer were randomly divided into treatment group (n = 28) and control group (n = 28). The treatment group was given omeprazole and the control group was treated with famotidine. Results: The effective rate was 96.4% in the treatment group and 71.4% in the control group, the difference between the two groups was statistically significant (P <0.05). The incidence of adverse reactions was 7.2% in the treatment group and 32.1% in the control group, with significant difference between the two groups (P <0.05). Conclusion: Omeprazole treatment of peptic ulcer with good efficacy and few adverse reactions, is worth clinical promotion.